"The findings build upon previous research by Walker and his team that shows sleep deprivation shuts down the brain's key planning and decision-making regions -- namely the prefrontal cortex -- while activating more primal neural functions such as the fight-or-flight reflex in the amygdala region of the brain."
If you've ever tried to make a complicated decision on no sleep, this is no surprise.
Source: http://www.sciencedaily.com/releases/2011/03/110323105211.htm
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